![]() ![]() For almost a century, neuroscientists assumed that once the mammalian brain matured, it generated no new neurons. The existence of adult neurogenesis in humans has been debated for decades. This plasticity is also important for understanding diseases like Alzheimer’s, which affect a patient’s memory, among other functions.” “This ability to repair itself is especially important when the brain is damaged, which is what happens during a stroke or brain injury. “Many mammals generate new neurons in their brains throughout their lifespans, which play a critical role in the brain’s plasticity, or ability to change and adapt over time,” says Hongjun Song, a Penn professor of neuroscience. The discovery paves the way for the deeper study of adult neurogenesis and its roles in memory, mood, behavior, and brain disorders. A team led by researchers at the Perelman School of Medicine has found that in the hippocampus, a key memory region of the brain, immature, plastic neurons are present in significant numbers throughout the human lifespan, findings they shared in the journal Nature. ![]()
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